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Drug Name | ASTX-660 |
Trade Name | |
Synonyms | ASTX660|ASTX 660 |
Drug Descriptions |
ASTX-660 is a SMAC mimetic that inhibits cIAP and XIAP, potentially resulting in tumor cell death (Cancer Res 2016;76(14 Suppl):Abstract nr 1287, PMID: 31900279). |
DrugClasses | SMAC Mimetic 8 |
CAS Registry Number | 1799328-86-1 |
NCIT ID | C123913 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
ASTX-660 | ASTX-660 | 0 | 2 |
ASTX-660 + Capecitabine | ASTX-660 Capecitabine | 0 | 0 |
ASTX-660 + Decitabine and Cedazuridine | ASTX-660 Decitabine and Cedazuridine | 0 | 1 |
ASTX-660 + Paclitaxel | ASTX-660 Paclitaxel | 0 | 0 |
ASTX-660 + Pembrolizumab | ASTX-660 Pembrolizumab | 0 | 1 |