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Drug Name | Intismeran autogene |
Trade Name | |
Synonyms | mRNA4157|mRNA 4157|V940|V-940|V 940|mRNA-4157 |
Drug Descriptions |
Intismeran autogene (mRNA-4157) is an mRNA-based lipid encapsulated personalized cancer vaccine encoding specific neoantigens, which potentially leads to enhanced anti-tumor immune response (Journal for ImmunoTherapy of Cancer 2020;8). |
DrugClasses | |
CAS Registry Number | 2931460-85-2 |
NCIT ID | C146813 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
BCG solution + Intismeran autogene | BCG solution Intismeran autogene | 0 | 1 |
Intismeran autogene | Intismeran autogene | 0 | 2 |
Intismeran autogene + Pembrolizumab | Intismeran autogene Pembrolizumab | 0 | 9 |