Pembrolizumab and berahyaluronidase alfa-pmph
Drug Detail

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Drug Name Pembrolizumab and berahyaluronidase alfa-pmph
Trade Name Keytruda Qlex
Synonyms MK 3475A|MK3475A|MK-3475A
Drug Descriptions

Keytruda Qlex (pembrolizumab and berahyaluronidase alfa-pmph) is a co-formulation of Keytruda (pembrolizumab) and berahyaluronidase alfa, which potentially enhances antitumor immune response (J Clin Oncol 2025 43: 16_suppl, TPS7090, NCI Drug Dictionary). Keytruda Qlex (pembrolizumab and berahyaluronidase alfa-pmph) is FDA-approved for use in adult and pediatric (12 years and older) solid tumor indications approved for the intravenous formulation of Keytruda (Pembrolizumab) (FDA.gov).

DrugClasses Immune Checkpoint Inhibitor 150 PD-L1/PD-1 antibody 132
CAS Registry Number NA
NCIT ID C200181

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Axitinib + Pembrolizumab + Pembrolizumab and berahyaluronidase alfa-pmph Axitinib Pembrolizumab Pembrolizumab and berahyaluronidase alfa-pmph 0 1
Carboplatin + Nab-paclitaxel + Pembrolizumab and berahyaluronidase alfa-pmph Carboplatin Nab-paclitaxel Pembrolizumab and berahyaluronidase alfa-pmph 0 1
Carboplatin + Paclitaxel + Pembrolizumab and berahyaluronidase alfa-pmph Carboplatin Paclitaxel Pembrolizumab and berahyaluronidase alfa-pmph 0 1
Carboplatin + Pembrolizumab + Pembrolizumab and berahyaluronidase alfa-pmph Carboplatin Pembrolizumab Pembrolizumab and berahyaluronidase alfa-pmph 0 1
Carboplatin + Pembrolizumab and berahyaluronidase alfa-pmph + Pemetrexed Disodium Carboplatin Pembrolizumab and berahyaluronidase alfa-pmph Pemetrexed Disodium 0 1
Cisplatin + Pembrolizumab + Pembrolizumab and berahyaluronidase alfa-pmph Cisplatin Pembrolizumab Pembrolizumab and berahyaluronidase alfa-pmph 0 1
Cisplatin + Pembrolizumab and berahyaluronidase alfa-pmph + Pemetrexed Disodium Cisplatin Pembrolizumab and berahyaluronidase alfa-pmph Pemetrexed Disodium 0 2
MK-1084 + Pembrolizumab and berahyaluronidase alfa-pmph MK-1084 Pembrolizumab and berahyaluronidase alfa-pmph 0 1
Nab-paclitaxel + Pembrolizumab + Pembrolizumab and berahyaluronidase alfa-pmph Nab-paclitaxel Pembrolizumab Pembrolizumab and berahyaluronidase alfa-pmph 0 1
Paclitaxel + Pembrolizumab + Pembrolizumab and berahyaluronidase alfa-pmph Paclitaxel Pembrolizumab Pembrolizumab and berahyaluronidase alfa-pmph 0 1
Pembrolizumab + Pembrolizumab and berahyaluronidase alfa-pmph Pembrolizumab Pembrolizumab and berahyaluronidase alfa-pmph 0 2
Pembrolizumab + Pembrolizumab and berahyaluronidase alfa-pmph + Pemetrexed Disodium Pembrolizumab Pembrolizumab and berahyaluronidase alfa-pmph Pemetrexed Disodium 0 1
Pembrolizumab and berahyaluronidase alfa-pmph Pembrolizumab and berahyaluronidase alfa-pmph 0 2


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