Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
| Drug Name | TNO155 |
| Trade Name | |
| Synonyms | TNO-155|TNO 155 |
| Drug Descriptions |
TNO155 is an inhibitor of PTPN11 (SHP2), which potentially blocks SHP2 signaling, thereby inhibiting activation of the MAPK pathway and subsequent tumor cell growth (PMID: 38032104, Cancer Res (2022) 82 (12_Supplement): 1054). |
| DrugClasses | SHP2 Inhibitor 21 |
| CAS Registry Number | NA |
| NCIT ID | C139559 |