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Drug Name | IDE196 |
Trade Name | |
Synonyms | LXS196|IDE 196|IDE-196|Darovasertib |
Drug Descriptions |
IDE196 (LXS196) is an inhibitor of protein kinase C (PKC), thereby blocking signaling pathways triggered by PKC, which may result in cell cycle arrest and apoptosis (AACR Annual Meeting 2019, Abstract CT068). |
DrugClasses | PKC Inhibitor (Pan) 11 |
CAS Registry Number | 1874276-76-2 |
NCIT ID | C124796 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Binimetinib + IDE196 | Binimetinib IDE196 | 0 | 0 |
Crizotinib + IDE196 | Crizotinib IDE196 | 0 | 1 |
IDE196 | IDE196 | 0 | 4 |
IDE196 + Siremadlin | IDE196 Siremadlin | 0 | 1 |
IDE196 + Trametinib | IDE196 Trametinib | 0 | 0 |