Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
Drug Name | AZD1390 |
Trade Name | |
Synonyms | AZD 1390|AZD-1390 |
Drug Descriptions |
AZD1390 is a selective inhibitor of ATM that is optimized for blood-brain barrier penetration, thus may preferentially sensitize CNS tumors for radiotherapy (Mol Cancer Ther 2018;17(1 Suppl):Abstract nr A104, PMID: 29938225, PMID: 31299316). |
DrugClasses | ATM Inhibitor 13 |
CAS Registry Number | 2089288-03-7 |
NCIT ID | C150167 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
AZD1390 | AZD1390 | 3 | 5 |
AZD1390 + Durvalumab | AZD1390 Durvalumab | 0 | 1 |
AZD1390 + GSK126 | AZD1390 GSK126 | 0 | 0 |
AZD1390 + Tazemetostat | AZD1390 Tazemetostat | 0 | 0 |