AZD1390
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| Drug Name | AZD1390 |
| Trade Name | |
| Synonyms | AZD 1390|AZD-1390 |
| Drug Descriptions |
AZD1390 is a selective inhibitor of ATM that is optimized for blood-brain barrier penetration, thus may preferentially sensitize CNS tumors for radiotherapy (Mol Cancer Ther 2018;17(1 Suppl):Abstract nr A104, PMID: 29938225, PMID: 31299316). |
| DrugClasses | ATM Inhibitor 13 |
| CAS Registry Number | 2089288-03-7 |
| NCIT ID | C150167 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| AZD1390 | AZD1390 | 3 | 7 |
| AZD1390 + Durvalumab | AZD1390 Durvalumab | 0 | 1 |
| AZD1390 + GSK126 | AZD1390 GSK126 | 0 | 0 |
| AZD1390 + Tazemetostat | AZD1390 Tazemetostat | 0 | 0 |
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