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Drug Name TSR-033
Trade Name
Synonyms TSR033|TSR 033
Drug Descriptions

TSR-033 is a humanized monoclonal antibody that targets LAG3 and inhibits binding of class II MHC molecules, potentially resulting in enhanced anti-tumor immune response, particularly in combination with other agents (PMID: 30587557).

DrugClasses LAG3 Antibody 18
CAS Registry Number NA
NCIT ID C142978

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Cobolimab + Dostarlimab-gxly + TSR-033 Cobolimab Dostarlimab-gxly TSR-033 0 1
Dostarlimab-gxly + TSR-033 Dostarlimab-gxly TSR-033 0 0
TSR-033 TSR-033 0 1
TSR-033 + unspecified PD-1 antibody TSR-033 unspecified PD-1 antibody 0 1


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