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Drug Name Cobolimab
Trade Name
Synonyms TSR-022
Drug Descriptions

Cobolimab (TSR-022) is a monoclonal antibody that targets T-cell immunoglobulin and mucin domain-3 protein (TIM-3, HAVCR2), potentially resulting in enhanced anti-tumor immune response (J Clin Oncol 40, no. 16_suppl (June 01, 2022) 2504).

DrugClasses Immune Checkpoint Inhibitor 149 TIM-3 Antibody 9
CAS Registry Number 2022215-65-0
NCIT ID C128627

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Cisplatin + Cobolimab + Dostarlimab-gxly + Pemetrexed Disodium Cisplatin Cobolimab Dostarlimab-gxly Pemetrexed Disodium 0 1
Cobolimab Cobolimab 0 2
Cobolimab + Docetaxel Cobolimab Docetaxel 0 1
Cobolimab + Docetaxel + Dostarlimab-gxly Cobolimab Docetaxel Dostarlimab-gxly 0 2
Cobolimab + Dostarlimab-gxly Cobolimab Dostarlimab-gxly 0 5
Cobolimab + Dostarlimab-gxly + TSR-033 Cobolimab Dostarlimab-gxly TSR-033 0 1
Cobolimab + Nivolumab Cobolimab Nivolumab 0 1
Cobolimab + unspecified PD-1 antibody Cobolimab unspecified PD-1 antibody 0 0


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