RP1
Drug Detail
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| Drug Name | RP1 |
| Trade Name | |
| Synonyms | Vusolimogene Oderparepvec|HSV-1 Engineered RP1|HSV-1 Oncolytic Viral Strain RP1 |
| Drug Descriptions |
RP1 is an engineered oncolytic type-I herpes simplex virus (HSV-1) strain that expresses a fusogenic glycoprotein (GALV-GP-R-) and GM-CSF, which potentially induces an anti-tumor immune response and tumor cell lysis (Cancer Res (2024) 84 (7_Supplement): CT003, NCI Drug Dictionary). |
| DrugClasses | |
| CAS Registry Number | NA |
| NCIT ID | C158074 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Atezolizumab + RP1 | Atezolizumab RP1 | 0 | 1 |
| Cemiplimab + RP1 | Cemiplimab RP1 | 0 | 1 |
| Nivolumab + RP1 | Nivolumab RP1 | 0 | 2 |
| Pembrolizumab + RP1 | Pembrolizumab RP1 | 0 | 1 |
| RP1 | RP1 | 0 | 5 |
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