CBM588
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| Drug Name | CBM588 |
| Trade Name | |
| Synonyms | CBM 588|C. butyricum CBM 588 probiotic strain|MIYAIRI 588 |
| Drug Descriptions |
CBM588 is a strain of Clostridium butyricum used as a probiotic, which induces the release of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL), potentially resulting in increased tumor cell death and decreased tumor growth (PMID: 23354042). |
| DrugClasses | Microbiome 9 |
| CAS Registry Number | 1034072-22-4 |
| NCIT ID | C154674 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Cabozantinib + CBM588 + Nivolumab | CBM588 Cabozantinib Nivolumab | 0 | 1 |
| CBM588 | CBM588 | 0 | 0 |
| CBM588 + Ipilimumab + Nivolumab | CBM588 Ipilimumab Nivolumab | 0 | 2 |
| CBM588 + Pembrolizumab | CBM588 Pembrolizumab | 0 | 1 |
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