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| Drug Name | Lazertinib |
| Trade Name | Lazcluze |
| Synonyms | GNS 1480|YH25448|JNJ-73841937|JNJ73841937|JNJ 73841937|YH 25448|YH-25448 |
| Drug Descriptions |
Lazcluze (lazertinib) is an irreversible protein kinase inhibitor with selective activity against mutant EGFR, which may lead to growth inhibition of EGFR-mutant tumor cells and reduced toxicity (PMID: 30670498, PMID: 32599977). Lazcluze (lazertinib) is FDA approved in combination with Rybrevant (amivantamab-vmjw) as first-line therapy in patients with locally advanced or metastatic non-small cell lung cancer harboring EGFR exon 19 deletions or EGFR L858R (FDA.gov) |
| DrugClasses | EGFR Inhibitor 3rd gen 26 |
| CAS Registry Number | 1903008-80-9 |
| NCIT ID | C148147 |
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