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Drug Name | S63845 |
Trade Name | |
Synonyms | MIK655|MIK-655|MIK 655|S-63845|S 63845 |
Drug Descriptions |
S63845 (MIK655) is a small molecule drug that binds to and inhibits Mcl1, leading to apoptosis in tumor cells (PMID: 27760111, PMID: 32513939). |
DrugClasses | MCL1 Inhibitor 18 |
CAS Registry Number | 1799633-27-4 |
NCIT ID | NA |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
A-1155463 + S63845 | A-1155463 S63845 | 0 | 0 |
A-1331852 + S63845 | A-1331852 S63845 | 0 | 0 |
ABT-737 + S63845 | ABT-737 S63845 | 0 | 0 |
Afatinib + ONO-7475 + S63845 | Afatinib ONO-7475 S63845 | 0 | 0 |
Azacitidine + S63845 | Azacitidine S63845 | 0 | 0 |
Capmatinib + S63845 | Capmatinib S63845 | 0 | 0 |
Docetaxel + S63845 | Docetaxel S63845 | 0 | 0 |
DT2216 + S63845 | DT2216 S63845 | 0 | 0 |
Erlotinib + ONO-7475 + S63845 | Erlotinib ONO-7475 S63845 | 0 | 0 |
Erlotinib + S63845 | Erlotinib S63845 | 0 | 0 |
Gefitinib + ONO-7475 + S63845 | Gefitinib ONO-7475 S63845 | 0 | 0 |
Lapatinib + S63845 | Lapatinib S63845 | 0 | 0 |
Lazertinib + ONO-7475 + S63845 | Lazertinib ONO-7475 S63845 | 0 | 0 |
Navitoclax + S63845 | Navitoclax S63845 | 0 | 0 |
ONO-7475 + Osimertinib + S63845 | ONO-7475 Osimertinib S63845 | 0 | 0 |
S63845 | S63845 | 1 | 0 |
S63845 + Trametinib | S63845 Trametinib | 4 | 0 |
S63845 + Trastuzumab | S63845 Trastuzumab | 0 | 0 |
S63845 + Vemurafenib | S63845 Vemurafenib | 1 | 0 |
S63845 + Venetoclax | S63845 Venetoclax | 0 | 0 |