Molecular Profile Detail

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Profile Name PDGFRB rearrange
Gene Variant Detail

PDGFRB rearrange (unknown)

Relevant Treatment Approaches PDGFR Inhibitor (Pan) PDGFR-beta Inhibitor

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Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT03801434 Phase II Ruxolitinib Ruxolitinib in Treating Patients with Hypereosinophilic Syndrome or Primary Eosinophilic Disorders Recruiting USA 0
NCT02029001 Phase II Durvalumab + Tremelimumab Olaparib Nilotinib Adapting Treatment to the Tumor Molecular Alterations for Patients With Advanced Solid Tumors: MyOwnSpecificTreatment (MOST plus) Recruiting FRA 0
NCT03862157 Phase Ib/II Azacitidine + MLN4924 + Venetoclax Azacitidine, Venetoclax, and Pevonedistat in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia Active, not recruiting USA 0
NCT02268253 Phase II Tagraxofusp-erzs Tagraxofusp (SL-401) in Patients With CMML or MF Completed USA | CAN 0
NCT05768711 Phase II Azacitidine + Venetoclax Azacitidine Combined With Venetoclax in Patients With Higher-risk Chronic Myelomonocytic Leukemia (AVENHIR) (AVENHIR) Active, not recruiting FRA 0
NCT01831726 Phase II Dovitinib Dovitinib for Patients With Tumor Pathway Activations Inhibited by Dovitinib Completed USA 0
NCT04546399 Phase II Blinatumomab + Methotrexate + Nivolumab Dexamethasone + Pegaspargase + Vincristine Sulfate Blinatumomab + Methotrexate Cyclophosphamide + Cytarabine + Dexamethasone + Etoposide + Leucovorin + Mercaptopurine + Methotrexate + Thioguanine + Vincristine Sulfate Blinatumomab + Cytarabine + Dexamethasone + Hydrocortisone Sodium Succinate + Leucovorin + Methotrexate + Nivolumab Blinatumomab + Dexamethasone + Methotrexate Blinatumomab + Cytarabine + Dexamethasone + Hydrocortisone Sodium Succinate + Methotrexate Blinatumomab + Cytarabine + Dexamethasone + Hydrocortisone Sodium Succinate + Methotrexate + Nivolumab Cytarabine + Dexamethasone + Doxorubicin + Hydrocortisone Sodium Succinate + Methotrexate + Pegaspargase + Vincristine Sulfate Blinatumomab + Dexamethasone + Methotrexate + Nivolumab Dexamethasone + Mercaptopurine + Methotrexate + Vincristine Sulfate A Study to Compare Blinatumomab Alone to Blinatumomab With Nivolumab in Patients Diagnosed With First Relapse B-Cell Acute Lymphoblastic Leukemia (B-ALL) Recruiting USA | CAN | AUS 1