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| Drug Name | Inlexisertib |
| Trade Name | |
| Synonyms | DCC 3116|DCC3116|DCC-3116 |
| Drug Descriptions |
Inlexisertib selectively inhibits ULK1/2, leading to decreased phosphorylation of its substrate ATG13 and inhibition of autophagosome formation, and may lead to inhibition of tumor cell growth (Mol Cancer Ther 2019;18(12 Suppl):Abstract nr B129). |
| DrugClasses | |
| CAS Registry Number | 2543673-19-2 |
| NCIT ID | C180331 |
| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Afatinib + Inlexisertib | Afatinib Inlexisertib | 0 | 0 |
| Binimetinib + Inlexisertib | Binimetinib Inlexisertib | 0 | 0 |
| Cetuximab + Encorafenib + Inlexisertib | Cetuximab Encorafenib Inlexisertib | 0 | 0 |
| Inlexisertib | Inlexisertib | 0 | 1 |
| Inlexisertib + Osimertinib | Inlexisertib Osimertinib | 0 | 0 |
| Inlexisertib + Ripretinib | Inlexisertib Ripretinib | 0 | 1 |
| Inlexisertib + Sotorasib | Inlexisertib Sotorasib | 0 | 1 |
| Inlexisertib + Trametinib | Inlexisertib Trametinib | 0 | 0 |