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| Drug Name | Encorafenib |
| Trade Name | Braftovi |
| Synonyms | LGX818 |
| Drug Descriptions |
Braftovi (encorafenib) is an inhibitor of Raf kinase with selective activity against BRAF V600E, resulting in growth inhibition (PMID: 24864047). Braftovi (encorafenib) is FDA approved for use in combination with Mektovi (binimetinib) in patients with unresectable or metastatic melanoma with a BRAF V600E or V600K mutation, and in patients with metastatic non-small cell lung cancer harboring BRAF V600E, and in combination with Erbitux (cetuximab) in patients with metastatic colorectal cancer with BRAF V600E (FDA.gov). |
| DrugClasses | BRAF Inhibitor 25 |
| CAS Registry Number | 1269440-17-6 |
| NCIT ID | C98283 |
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