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Drug Name | DFF332 |
Trade Name | |
Synonyms | DFF 332|DFF-332 |
Drug Descriptions |
DFF332 inhibits HIF-2alpha and blocks its DNA binding, which may lead to downregulation of HIF-2alpha target genes involved in tumor cell growth and survival (NCI Drug Dictionary). |
DrugClasses | HIF2A Inhibitor 6 |
CAS Registry Number | NA |
NCIT ID | C180826 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
DFF332 | DFF332 | 0 | 1 |
DFF332 + Everolimus | DFF332 Everolimus | 0 | 1 |
DFF332 + Spartalizumab + Taminadenant | DFF332 Spartalizumab Taminadenant | 0 | 1 |