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Drug Name | Taminadenant |
Trade Name | |
Synonyms | NIR178|PBF-509 |
Drug Descriptions |
Taminadenant binds to and inhibits the adenosine A2A (ADORA2A) receptor on immune cells, resulting in activation of an anti-tumor immune response by blocking binding of the immunosuppressive metabolite, adenosine (PMID: 29758241, PMID: 28582704). |
DrugClasses | Adenosine Targeting 23 |
CAS Registry Number | 1337962-47-6 |
NCIT ID | C121664 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
DFF332 + Spartalizumab + Taminadenant | DFF332 Spartalizumab Taminadenant | 0 | 1 |
Ieramilimab + Spartalizumab + Taminadenant | Ieramilimab Spartalizumab Taminadenant | 0 | 1 |
KAZ954 + Taminadenant | KAZ954 Taminadenant | 0 | 1 |
NZV930 + Spartalizumab + Taminadenant | NZV930 Spartalizumab Taminadenant | 0 | 1 |
NZV930 + Taminadenant | NZV930 Taminadenant | 0 | 1 |
Spartalizumab + Taminadenant | Spartalizumab Taminadenant | 0 | 2 |
Taminadenant | Taminadenant | 0 | 1 |