To all our CKB CORE users, don’t miss the latest new features now available! Register for a free CORE account here and then login for access. Feel free to contact us at ckbsupport@genomenon.com if you have any questions!

Drug Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Drug Name BGB-11417
Trade Name
Synonyms BGB 11417|BGB11417|Sonrotoclax
Drug Descriptions

BGB-11417 selectively inhibits Bcl2, which potentially leads to decreased tumor cell proliferation and inhibition of tumor growth (Cancer Res 2020;80(16 Suppl):Abstract nr 3077).

DrugClasses BCL2 inhibitor 27
CAS Registry Number NA
NCIT ID C175489

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Therapy Name Drugs Efficacy Evidence Clinical Trials
Azacitidine + BGB-11417 Azacitidine BGB-11417 0 1
Azacitidine + BGB-11417 + Posaconazole Azacitidine BGB-11417 Posaconazole 0 0
BGB-11417 BGB-11417 0 3
BGB-11417 + BGB-16673 BGB-11417 BGB-16673 0 1
BGB-11417 + Carfilzomib + Dexamethasone BGB-11417 Carfilzomib Dexamethasone 0 1
BGB-11417 + Dexamethasone BGB-11417 Dexamethasone 0 1
BGB-11417 + Obinutuzumab + Zanubrutinib BGB-11417 Obinutuzumab Zanubrutinib 0 1
BGB-11417 + Rituximab BGB-11417 Rituximab 0 1
BGB-11417 + Rituximab + Zanubrutinib BGB-11417 Rituximab Zanubrutinib 0 1
BGB-11417 + Zanubrutinib BGB-11417 Zanubrutinib 0 7


Additional content available in Icon for CKB-BoostCKB BOOST