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Drug Name BGB-11417
Trade Name
Synonyms BGB 11417|BGB11417|Sonrotoclax
Drug Descriptions

BGB-11417 selectively inhibits Bcl2, which potentially leads to decreased tumor cell proliferation and inhibition of tumor growth (Cancer Res 2020;80(16 Suppl):Abstract nr 3077).

DrugClasses BCL2 inhibitor 27
CAS Registry Number NA
NCIT ID C175489

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Azacitidine + BGB-11417 Azacitidine BGB-11417 0 1
Azacitidine + BGB-11417 + Posaconazole Azacitidine BGB-11417 Posaconazole 0 0
BGB-11417 BGB-11417 0 3
BGB-11417 + Carfilzomib + Dexamethasone BGB-11417 Carfilzomib Dexamethasone 0 1
BGB-11417 + Dexamethasone BGB-11417 Dexamethasone 0 1
BGB-11417 + Zanubrutinib BGB-11417 Zanubrutinib 0 3


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