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Drug Name | Zanubrutinib |
Trade Name | Brukinsa |
Synonyms | BGB-3111 |
Drug Descriptions |
Brukinsa (zanubrutinib) inhibits Bruton tyrosine kinase (BTK), leading to decreased B-cell activation and reduced growth of BTK over-expressing cells (PMID: 31378456). Brukinsa (zanubrutinib) is FDA approved for use in patients with mantle cell lymphoma, Waldenstrom’s macroglobulinemia, and chronic lymphocytic leukemia or small lymphocytic lymphoma (CLL/SLL) (FDA.gov). |
DrugClasses | BTK inhibitor 37 |
CAS Registry Number | 1691249-45-2 |
NCIT ID | C141428 |