GSK5733584
Drug Detail
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| Drug Name | GSK5733584 |
| Trade Name | |
| Synonyms | GSK 5733584|GSK-5733584|HS-20089 |
| Drug Descriptions |
GSK5733584 is an antibody-drug conjugate (ADC) comprising a monoclonal antibody targeting VTCN1 (B7-H4) linked to a topoisomerase I inhibitor, which potentially induces apoptosis in VTCN1 (B7-H4)-expressing tumor cells (Cancer Res (2025) 85 (8_Supplement_2): CT188, NCI Drug Dictionary). |
| DrugClasses | |
| CAS Registry Number | NA |
| NCIT ID | C210991 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Bevacizumab + Dostarlimab-gxly + GSK5733584 | Bevacizumab Dostarlimab-gxly GSK5733584 | 0 | 0 |
| Bevacizumab + GSK5733584 | Bevacizumab GSK5733584 | 0 | 1 |
| Dostarlimab-gxly + GSK5733584 | Dostarlimab-gxly GSK5733584 | 0 | 2 |
| GSK5733584 | GSK5733584 | 0 | 3 |
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