SIAIS562055
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| Drug Name | SIAIS562055 |
| Trade Name | |
| Synonyms | SIAIS-562055|SIAIS 562055 |
| Drug Descriptions |
SIAIS562055 is a proteolysis targeting chimera (PROTAC) targeting SOS1, which potentially decreases downstream Erk signaling, tumor cell proliferation, and tumor growth (PMID: 39437162). |
| DrugClasses | SOS1 Inhibitor 17 |
| CAS Registry Number | NA |
| NCIT ID | NA |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Adagrasib + SIAIS562055 | Adagrasib SIAIS562055 | 0 | 0 |
| Imatinib + SIAIS562055 | Imatinib SIAIS562055 | 0 | 0 |
| MRTX-1133 + SIAIS562055 | MRTX-1133 SIAIS562055 | 0 | 0 |
| Nilotinib + SIAIS562055 | Nilotinib SIAIS562055 | 0 | 0 |
| Olverembatinib + SIAIS562055 | Olverembatinib SIAIS562055 | 0 | 0 |
| SIAIS562055 | SIAIS562055 | 0 | 0 |
| SIAIS562055 + Sotorasib | SIAIS562055 Sotorasib | 0 | 0 |
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