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Drug Name | Olverembatinib |
Trade Name | |
Synonyms | HQP 1351|HQP-1351|GZD824 dimesylate|GZD824|HQP1351 |
Drug Descriptions |
Olverembatinib (HQP1351) is a third-generation BCR-ABL inhibitor and multikinase inhibitor that inhibits KIT, ABL1, FGFR1, FLT3, and PDGFRA (PMID: 32247263), which potentially induces apoptosis, and inhibits tumor cell growth, migration, and invasion (PMID: 31673329). |
DrugClasses | ABL1 Inhibitor 8 FGFR1 Inhibitor 28 FLT3 Inhibitor 69 KIT Inhibitor 57 PDGFR-alpha Inhibitor 9 |
CAS Registry Number | 1421783-64-3 |
NCIT ID | C165549 |