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| Drug Name | ALTA3263 |
| Trade Name | |
| Synonyms | ALTA-3263|ALTA 3263 |
| Drug Descriptions |
ALTA3263 is a an isoform-selective inhibitor of KRAS with activity against KRAS G12C, KRAS G12D, and KRAS G12V, which reduces downstream signaling and potentially decreases tumor cell viability and tumor growth (Eur J Cancer 211 (2024): 114537). |
| DrugClasses | KRAS G12C inhibitor 36 KRAS G12D Inhibitor 25 |
| CAS Registry Number | NA |
| NCIT ID | NA |
| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| ALTA3263 | ALTA3263 | 0 | 1 |
| ALTA3263 + Cetuximab | ALTA3263 Cetuximab | 0 | 1 |