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Drug Name Canakinumab
Trade Name Ilaris
Synonyms ACZ-885
Drug Descriptions

Ilaris (canakinumab) is a monoclonal antibody against interleukin-1beta, which has anti-inflammatory activity and may decrease tumor progression (PMID: 28855077).

DrugClasses
CAS Registry Number 914613-48-2
NCIT ID C80971

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Azacitidine + Canakinumab Azacitidine Canakinumab 0 1
Canakinumab Canakinumab 0 5
Canakinumab + Carboplatin + Nab-paclitaxel + Pembrolizumab Canakinumab Carboplatin Nab-paclitaxel Pembrolizumab 0 0
Canakinumab + Carboplatin + Paclitaxel + Pembrolizumab Canakinumab Carboplatin Paclitaxel Pembrolizumab 0 0
Canakinumab + Carboplatin + Pembrolizumab + Pemetrexed Disodium Canakinumab Carboplatin Pembrolizumab Pemetrexed Disodium 0 0
Canakinumab + Carboplatin + Spartalizumab Canakinumab Carboplatin Spartalizumab 0 1
Canakinumab + Cisplatin + Pembrolizumab + Pemetrexed Disodium Canakinumab Cisplatin Pembrolizumab Pemetrexed Disodium 0 0
Canakinumab + Cisplatin + Pemetrexed Disodium + Spartalizumab Canakinumab Cisplatin Pemetrexed Disodium Spartalizumab 0 1
Canakinumab + Darbepoetin Alfa Canakinumab Darbepoetin Alfa 0 1
Canakinumab + Docetaxel Canakinumab Docetaxel 0 1
Canakinumab + Durvalumab Canakinumab Durvalumab 0 1
Canakinumab + Gemcitabine + Nab-paclitaxel + Spartalizumab Canakinumab Gemcitabine Nab-paclitaxel Spartalizumab 0 1
Canakinumab + Gemcitabine + Nab-paclitaxel + Tislelizumab Canakinumab Gemcitabine Nab-paclitaxel Tislelizumab 0 1
Canakinumab + Ieramilimab + Spartalizumab Canakinumab Ieramilimab Spartalizumab 0 1
Canakinumab + Pembrolizumab Canakinumab Pembrolizumab 0 2
Canakinumab + Sabatolimab Canakinumab Sabatolimab 0 1
Canakinumab + Spartalizumab Canakinumab Spartalizumab 0 3


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