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Drug Name Sotrastaurin
Trade Name
Synonyms AEB071
Drug Descriptions

Sotrastaurin (AEB071) is a pan-PKC inhibitor, which induces cell cycle arrest and apoptosis (PMID: 19491325, PMID: 31261030).

DrugClasses PKC Inhibitor (Pan) 11
CAS Registry Number 425637-18-9
NCIT ID C80630

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Alpelisib + Sotrastaurin Alpelisib Sotrastaurin 0 1
Binimetinib + Sotrastaurin Binimetinib Sotrastaurin 0 1
CGM097 + Sotrastaurin CGM097 Sotrastaurin 0 0
Everolimus + Sotrastaurin Everolimus Sotrastaurin 0 1
PD-0325901 + Sotrastaurin PD-0325901 Sotrastaurin 0 0
Sotrastaurin Sotrastaurin 0 2


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