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Drug Name | Ensartinib |
Trade Name | |
Synonyms | X-396 |
Drug Descriptions |
Ensartinib (X-396) is a small molecule inhibitor of ALK, which inhibits downstream signaling and potentially leads to decreased growth of ALK-expressing tumors (PMID: 21613408, PMID: 31628085). |
DrugClasses | ALK Inhibitor 32 |
CAS Registry Number | 1370651-20-9 |
NCIT ID | C102754 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Bevacizumab + Carboplatin + Ensartinib + Pemetrexed Disodium | Bevacizumab Carboplatin Ensartinib Pemetrexed Disodium | 0 | 1 |
Carboplatin + Ensartinib | Carboplatin Ensartinib | 0 | 1 |
Cisplatin + Ensartinib | Cisplatin Ensartinib | 0 | 1 |
Denosumab + Ensartinib | Denosumab Ensartinib | 0 | 0 |
Durvalumab + Ensartinib | Durvalumab Ensartinib | 0 | 1 |
Ensartinib | Ensartinib | 45 | 8 |
Ensartinib + Fruquintinib | Ensartinib Fruquintinib | 0 | 0 |
Ensartinib + Pralsetinib | Ensartinib Pralsetinib | 0 | 0 |
Ensartinib + Sirolimus | Ensartinib Sirolimus | 1 | 0 |