Drug Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Drug Name Tivozanib
Trade Name Fotivda
Synonyms AV-951|AV951|KIL-8951|KRN 951|KRN-951
Drug Descriptions

Fotivda (tivozanib) inhibits VEGFR1-3, which may result in decreased tumor angiogenesis and proliferation and increased cell death (PMID: 23788831, PMID: 31810797, PMID: 32547647). Fotivda(tivozanib) is FDA approved for use in adult patients with relapsed or refractory advanced renal cell carcinoma who have received two or more prior systemic therapies (FDA.gov).

DrugClasses VEGFR Inhibitor (Pan) 36
CAS Registry Number 475108-18-0
NCIT ID C85444

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Therapy Name Drugs Efficacy Evidence Clinical Trials
23814 + Tivozanib 23814 Tivozanib 0 0
Atezolizumab + Tivozanib Atezolizumab Tivozanib 0 1
Durvalumab + Tivozanib Durvalumab Tivozanib 0 1
Enzalutamide + Tivozanib Enzalutamide Tivozanib 0 1
Fluorouracil + Leucovorin + Oxaliplatin + Tivozanib Fluorouracil Leucovorin Oxaliplatin Tivozanib 0 0
Nivolumab + Tivozanib Nivolumab Tivozanib 0 2
PLX4720 + Tivozanib PLX4720 Tivozanib 1 0
Tivozanib Tivozanib 1 6


Additional content available in CKB BOOST