Nazartinib
Drug Detail
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| Drug Name | Nazartinib |
| Trade Name | |
| Synonyms | EGF816|EGF-816 |
| Drug Descriptions |
Nazartinib (EGF816) is a third generation EGFR inhibitor with selectivity towards mutant forms of EGFR, resulting in inhibition of tumor cell growth (PMID: 27433829, PMID: 31954624). |
| DrugClasses | EGFR Inhibitor 3rd gen 28 |
| CAS Registry Number | 1508250-71-2 |
| NCIT ID | C115109 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Capmatinib + Nazartinib | Capmatinib Nazartinib | 0 | 3 |
| Gefitinib + Nazartinib | Gefitinib Nazartinib | 0 | 2 |
| LXH 254 + Nazartinib | LXH 254 Nazartinib | 0 | 1 |
| Nazartinib | Nazartinib | 0 | 1 |
| Nazartinib + Nivolumab | Nazartinib Nivolumab | 0 | 1 |
| Nazartinib + Ribociclib | Nazartinib Ribociclib | 0 | 1 |
| Nazartinib + Spartalizumab | Nazartinib Spartalizumab | 0 | 1 |
| Nazartinib + Trametinib | Nazartinib Trametinib | 0 | 2 |
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