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| Drug Name | CPI-0610 |
| Trade Name | |
| Synonyms | CPI0610|pelabresib |
| Drug Descriptions |
CPI-0610 is a small molecule that binds to BET bromodomains and inhibits interaction with acetylated histones, resulting in regulation of BET-dependent gene expression and anti-tumor effects (PMID: 26815195, PMID: 31729905). |
| DrugClasses | BET Inhibitor (Pan) 32 |
| CAS Registry Number | 1380087-89-7 |
| NCIT ID | C111901 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| CPI-0610 | CPI-0610 | 0 | 4 |
| CPI-0610 + Dasatinib | CPI-0610 Dasatinib | 0 | 0 |
| CPI-0610 + Dasatinib + Rucaparib | CPI-0610 Dasatinib Rucaparib | 0 | 0 |
| CPI-0610 + Doxorubicin | CPI-0610 Doxorubicin | 0 | 0 |
| CPI-0610 + Rucaparib | CPI-0610 Rucaparib | 0 | 0 |
| CPI-0610 + Ruxolitinib | CPI-0610 Ruxolitinib | 0 | 2 |
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