Pelabresib
Drug Detail
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| Drug Name | Pelabresib |
| Trade Name | |
| Synonyms | CPI0610|CPI-0610|CPI0610 |
| Drug Descriptions |
Pelabresib (CPI-0610) is a small molecule that binds to BET bromodomains and inhibits interaction with acetylated histones, potentially resulting in regulation of BET-dependent gene expression and antitumor activity (PMID: 26815195, PMID: 31729905). |
| DrugClasses | BET Inhibitor (Pan) 33 |
| CAS Registry Number | 1380087-89-7 |
| NCIT ID | C111901 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Dasatinib + Pelabresib | Dasatinib Pelabresib | 0 | 0 |
| Dasatinib + Pelabresib + Rucaparib | Dasatinib Pelabresib Rucaparib | 0 | 0 |
| Doxorubicin + Pelabresib | Doxorubicin Pelabresib | 0 | 0 |
| Pelabresib | Pelabresib | 0 | 4 |
| Pelabresib + Rucaparib | Pelabresib Rucaparib | 0 | 0 |
| Pelabresib + Ruxolitinib | Pelabresib Ruxolitinib | 0 | 2 |
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