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Drug Name Ceralasertib
Trade Name
Synonyms AZD6738|AZD-6738
Drug Descriptions

Ceralasertib (AZD6738) is an inhibitor of ATR, which may enhance the sensitivity of chemotherapeutic agents, potentially resulting in tumor regression (PMID: 26517239, PMID: 31836456).

DrugClasses ATR Inhibitor 16
CAS Registry Number 1352226-88-0
NCIT ID C111993

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Acalabrutinib + Ceralasertib Acalabrutinib Ceralasertib 0 1
Camptothecin + Ceralasertib Camptothecin Ceralasertib 0 0
Carboplatin + Ceralasertib Carboplatin Ceralasertib 0 1
Carboplatin + Ceralasertib + Durvalumab + Etoposide Carboplatin Ceralasertib Durvalumab Etoposide 0 1
Ceralasertib Ceralasertib 9 8
Ceralasertib + Cisplatin Ceralasertib Cisplatin 1 0
Ceralasertib + Cisplatin + Durvalumab + Etoposide Ceralasertib Cisplatin Durvalumab Etoposide 0 1
Ceralasertib + Durvalumab Ceralasertib Durvalumab 2 6
Ceralasertib + Durvalumab + Nab-paclitaxel Ceralasertib Durvalumab Nab-paclitaxel 0 1
Ceralasertib + Gemcitabine Ceralasertib Gemcitabine 0 1
Ceralasertib + Ibrutinib Ceralasertib Ibrutinib 2 0
Ceralasertib + LB-100 Ceralasertib LB-100 0 0
Ceralasertib + Niraparib Ceralasertib Niraparib 1 0
Ceralasertib + Olaparib Ceralasertib Olaparib 9 12
Ceralasertib + Paclitaxel Ceralasertib Paclitaxel 0 0
Ceralasertib + Radiotherapy Ceralasertib Radiotherapy 4 0
Ceralasertib + Saruparib Ceralasertib Saruparib 0 0
Ceralasertib + STP-B Ceralasertib STP-B 0 0
Ceralasertib + Talazoparib Ceralasertib Talazoparib 1 0
Ceralasertib + Trastuzumab deruxtecan Ceralasertib Trastuzumab deruxtecan 0 1


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