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Drug Name | Bemarituzumab |
Trade Name | |
Synonyms | FPA144 |
Drug Descriptions |
Bemarituzumab (FPA144) is a monoclonal antibody against FGFR2 isoform B, which prevents ligand interaction and induces cell mediated cytotoxicity, potentially inhibiting proliferation and promoting apoptosis in cancer cells expressing FGFR2 isoform B (J Clin Oncol 32, 2014 (suppl; abstr e15074, PMID: 31094225, PMID: 32167861). |
DrugClasses | FGFR2 Antibody 3 |
CAS Registry Number | 1952272-74-0 |
NCIT ID | C120040 |