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Drug Name | A-1210477 |
Trade Name | |
Synonyms | AOB5551 |
Drug Descriptions |
A-1210477 binds to and inhibits MCL1, resulting in increased apoptosis of MCL1-dependent tumor cells (PMID: 25590800, PMID: 30647404, PMID: 32486166). |
DrugClasses | MCL1 Inhibitor 18 |
CAS Registry Number | 1668553-26-1 |
NCIT ID | NA |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
A-1210477 | A-1210477 | 1 | 0 |
A-1210477 + A-1331852 | A-1210477 A-1331852 | 0 | 0 |
A-1210477 + Cobimetinib | A-1210477 Cobimetinib | 0 | 0 |
A-1210477 + Cobimetinib + Vemurafenib | A-1210477 Cobimetinib Vemurafenib | 0 | 0 |
A-1210477 + G-TPP | A-1210477 G-TPP | 0 | 0 |
A-1210477 + LAM-003 | A-1210477 LAM-003 | 0 | 0 |
A-1210477 + Lapatinib + WEHI-539 | A-1210477 Lapatinib WEHI-539 | 0 | 0 |
A-1210477 + Vemurafenib | A-1210477 Vemurafenib | 0 | 0 |
A-1210477 + Venetoclax | A-1210477 Venetoclax | 1 | 0 |
A-1210477 + WEHI-539 | A-1210477 WEHI-539 | 1 | 0 |