LAM-003
Drug Detail
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| Drug Name | LAM-003 |
| Trade Name | |
| Synonyms | LAM003|LAM 003 |
| Drug Descriptions |
LAM-003 is a prodrug that is metabolized by esterases into the active HSP90 inhibitor drug, LAM-003A, which potentially induces cytotoxicity, and inhibits viability and tumor growth (PMID: 31751472). |
| DrugClasses | HSP90 Inhibitor 35 |
| CAS Registry Number | NA |
| NCIT ID | C152979 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| A-1210477 + LAM-003 | A-1210477 LAM-003 | 0 | 0 |
| Crenolanib + LAM-003 | Crenolanib LAM-003 | 0 | 0 |
| Cytarabine + LAM-003 | Cytarabine LAM-003 | 1 | 0 |
| Daunorubicin + LAM-003 | Daunorubicin LAM-003 | 1 | 0 |
| Gilteritinib + LAM-003 | Gilteritinib LAM-003 | 1 | 0 |
| GSK690693 + LAM-003 | GSK690693 LAM-003 | 0 | 0 |
| LAM-003 | LAM-003 | 6 | 2 |
| LAM-003 + MK2206 | LAM-003 MK2206 | 0 | 0 |
| LAM-003 + Sorafenib | LAM-003 Sorafenib | 0 | 0 |
| LAM-003 + Tazemetostat | LAM-003 Tazemetostat | 1 | 0 |
| LAM-003 + Venetoclax | LAM-003 Venetoclax | 1 | 0 |
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