Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
Drug Name | TAK-632 |
Trade Name | |
Synonyms | TAK 632|TAK632 |
Drug Descriptions |
TAK-632 is an inhibitor of Raf, which has been shown to suppress the kinase activity of the Raf dimer thereby resulting in diminished paradoxical activation of Raf (PMID: 24121489, PMID: 31734178). |
DrugClasses | RAF Inhibitor (Pan) 28 |
CAS Registry Number | 1228591-30-7 |
NCIT ID | NA |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Bosutinib + TAK-632 | Bosutinib TAK-632 | 0 | 0 |
Osimertinib + TAK-632 | Osimertinib TAK-632 | 0 | 0 |
PLX4720 + TAK-632 | PLX4720 TAK-632 | 1 | 0 |
Saracatinib + TAK-632 | Saracatinib TAK-632 | 0 | 0 |
TAK-632 | TAK-632 | 14 | 0 |