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Drug Name | Pimasertib |
Trade Name | |
Synonyms | AS703026|MSC1936369B |
Drug Descriptions |
Pimasertib (MSC1936369B) binds to and inhibits MEK1/2, preventing activation of downstream targets and potentially reducing tumor cell proliferation (PMID: 23587417, PMID: 31870556). |
DrugClasses | MEK inhibitor (Pan) 26 MEK1 Inhibitor 26 MEK2 Inhibitor 24 |
CAS Registry Number | 1236699-92-5 |
NCIT ID | C84864 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Bintrafusp alfa + Pimasertib | Bintrafusp alfa Pimasertib | 0 | 1 |
Cetuximab + Pimasertib | Cetuximab Pimasertib | 1 | 0 |
Dactolisib + Pimasertib | Dactolisib Pimasertib | 0 | 0 |
Everolimus + Pimasertib | Everolimus Pimasertib | 3 | 0 |
Gemcitabine + Pimasertib | Gemcitabine Pimasertib | 0 | 0 |
Lifirafenib + Pimasertib | Lifirafenib Pimasertib | 1 | 0 |
Palbociclib + Pimasertib | Palbociclib Pimasertib | 0 | 0 |
Pimasertib | Pimasertib | 4 | 3 |
Pimasertib + Regorafenib | Pimasertib Regorafenib | 3 | 0 |
Pimasertib + SAR405838 | Pimasertib SAR405838 | 2 | 0 |
Pimasertib + Sorafenib | Pimasertib Sorafenib | 3 | 0 |
Pimasertib + Tovorafenib | Pimasertib Tovorafenib | 0 | 1 |
Pimasertib + Voxtalisib | Pimasertib Voxtalisib | 0 | 0 |