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| Drug Name | Pimasertib |
| Trade Name | |
| Synonyms | AS703026|MSC1936369B |
| Drug Descriptions |
Pimasertib (MSC1936369B) binds to and inhibits MEK1/2, preventing activation of downstream targets and potentially reducing tumor cell proliferation (PMID: 23587417, PMID: 31870556). |
| DrugClasses | MEK inhibitor (Pan) 27 MEK1 Inhibitor 27 MEK2 Inhibitor 25 |
| CAS Registry Number | 1236699-92-5 |
| NCIT ID | C84864 |
| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Bintrafusp alfa + Pimasertib | Bintrafusp alfa Pimasertib | 0 | 1 |
| Cetuximab + Pimasertib | Cetuximab Pimasertib | 1 | 0 |
| Dactolisib + Pimasertib | Dactolisib Pimasertib | 0 | 0 |
| Everolimus + Pimasertib | Everolimus Pimasertib | 3 | 0 |
| Gemcitabine + Pimasertib | Gemcitabine Pimasertib | 0 | 0 |
| Lifirafenib + Pimasertib | Lifirafenib Pimasertib | 1 | 0 |
| Palbociclib + Pimasertib | Palbociclib Pimasertib | 0 | 0 |
| Pimasertib | Pimasertib | 4 | 2 |
| Pimasertib + Regorafenib | Pimasertib Regorafenib | 3 | 0 |
| Pimasertib + SAR405838 | Pimasertib SAR405838 | 2 | 0 |
| Pimasertib + Sorafenib | Pimasertib Sorafenib | 3 | 0 |
| Pimasertib + TAK-632 | Pimasertib TAK-632 | 0 | 0 |
| Pimasertib + Tovorafenib | Pimasertib Tovorafenib | 0 | 1 |
| Pimasertib + Voxtalisib | Pimasertib Voxtalisib | 0 | 0 |