Drug Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Drug Name Pimasertib
Trade Name
Synonyms AS703026|MSC1936369B
Drug Descriptions

Pimasertib (MSC1936369B) binds to and inhibits MEK1/2, preventing activation of downstream targets and potentially reducing tumor cell proliferation (PMID: 23587417, PMID: 31870556).

DrugClasses MEK inhibitor (Pan) 26 MEK1 Inhibitor 26 MEK2 Inhibitor 24
CAS Registry Number 1236699-92-5
NCIT ID C84864

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Therapy Name Drugs Efficacy Evidence Clinical Trials
Bintrafusp alfa + Pimasertib Bintrafusp alfa Pimasertib 0 1
Cetuximab + Pimasertib Cetuximab Pimasertib 1 0
Dactolisib + Pimasertib Dactolisib Pimasertib 0 0
Everolimus + Pimasertib Everolimus Pimasertib 3 0
Gemcitabine + Pimasertib Gemcitabine Pimasertib 0 0
Lifirafenib + Pimasertib Lifirafenib Pimasertib 1 0
Palbociclib + Pimasertib Palbociclib Pimasertib 0 0
Pimasertib Pimasertib 4 3
Pimasertib + Regorafenib Pimasertib Regorafenib 3 0
Pimasertib + SAR405838 Pimasertib SAR405838 2 0
Pimasertib + Sorafenib Pimasertib Sorafenib 3 0
Pimasertib + Tovorafenib Pimasertib Tovorafenib 0 1
Pimasertib + Voxtalisib Pimasertib Voxtalisib 0 0


Additional content available in CKB BOOST