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| Drug Name | Pemigatinib |
| Trade Name | Pemazyre |
| Synonyms | INCB54828|INCB054828 |
| Drug Descriptions |
Pemazyre (pemigatinib) is a fibroblast growth factor receptor (FGFR) inhibitor that blocks FGFR1/2/3 signaling, which results in growth inhibition in tumor cells (PMID: 32203698). Pemazyre (pemigatinib) is FDA approved for use in patients with advanced or metastatic cholangiocarcinoma harboring FGFR2 fusion or rearrangement, and in adult patients with relapsed or refractory myeloid or lymphoid neoplasms harboring FGFR1 rearrangement (FDA.gov). |
| DrugClasses | FGFR1 Inhibitor 28 FGFR2 Inhibitor 23 FGFR3 Inhibitor 19 |
| CAS Registry Number | 1513857-77-6 |
| NCIT ID | C121553 |
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