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Drug Name | GSK2334470 |
Trade Name | |
Synonyms | GSK-470 |
Drug Descriptions |
GSK2334470 is a small molecule inhibitor of PDPK1, which subsequently results in suppression of Akt and may result in antiproliferative activity (PMID: 29658600, PMID: 32188393). |
DrugClasses | PDPK1 Inhibitor 10 |
CAS Registry Number | 1227911-45-6 |
NCIT ID | NA |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Alpelisib + GSK2334470 | Alpelisib GSK2334470 | 1 | 0 |
ARQ 751 + GSK2334470 | ARQ 751 GSK2334470 | 1 | 0 |
GSK2334470 | GSK2334470 | 0 | 0 |
GSK2334470 + GSK690693 | GSK2334470 GSK690693 | 1 | 0 |
GSK2334470 + Idelalisib | GSK2334470 Idelalisib | 1 | 0 |
GSK2334470 + Ipatasertib | GSK2334470 Ipatasertib | 1 | 0 |
GSK2334470 + Miransertib | GSK2334470 Miransertib | 2 | 0 |
GSK2334470 + MK2206 | GSK2334470 MK2206 | 1 | 0 |
GSK2334470 + Osimertinib | GSK2334470 Osimertinib | 0 | 0 |
GSK2334470 + Palbociclib | GSK2334470 Palbociclib | 0 | 0 |
GSK2334470 + Trametinib | GSK2334470 Trametinib | 2 | 0 |