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Drug Name | NZV930 |
Trade Name | |
Synonyms | SRF373|SRF-373|SRF 373|NZV 930|NZV-930 |
Drug Descriptions |
NZV930 is a monoclonal antibody against NT5E (CD73), resulting in activation of an anti-tumor immune response by preventing the conversion of AMP to adenosine in the tumor microenvironment (PMID: 31461341). |
DrugClasses | Adenosine Targeting 23 CD73 Antibody 12 |
CAS Registry Number | NA |
NCIT ID | C158132 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
KAZ954 + NZV930 | KAZ954 NZV930 | 0 | 1 |
NZV930 | NZV930 | 0 | 1 |
NZV930 + Spartalizumab | NZV930 Spartalizumab | 0 | 1 |
NZV930 + Spartalizumab + Taminadenant | NZV930 Spartalizumab Taminadenant | 0 | 1 |
NZV930 + Taminadenant | NZV930 Taminadenant | 0 | 1 |