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Drug Name | INCB001158 |
Trade Name | |
Synonyms | CB-1158|CB1158|CB 1158 |
Drug Descriptions |
INCB001158 (CB-1158) is a human arginase inhibitor that restores arginine levels in T-cells, thereby promoting T-cell proliferation and anti-tumor immunity (PMID: 32647818). |
DrugClasses | |
CAS Registry Number | 2095732-06-0 |
NCIT ID | C142866 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Cisplatin + Gemcitabine + INCB001158 | Cisplatin Gemcitabine INCB001158 | 0 | 1 |
Daratumumab + INCB001158 | Daratumumab INCB001158 | 0 | 1 |
Epacadostat + INCB001158 | Epacadostat INCB001158 | 0 | 1 |
Epacadostat + INCB001158 + Pembrolizumab | Epacadostat INCB001158 Pembrolizumab | 0 | 1 |
Fluorouracil + INCB001158 + Leucovorin + Oxaliplatin | Fluorouracil INCB001158 Leucovorin Oxaliplatin | 0 | 1 |
INCB001158 | INCB001158 | 0 | 1 |
INCB001158 + Nivolumab | INCB001158 Nivolumab | 0 | 1 |
INCB001158 + Paclitaxel | INCB001158 Paclitaxel | 0 | 1 |