Ubamatamab
Drug Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Drug Name Ubamatamab
Trade Name
Synonyms REGN-4018|REGN 4018|REGN4018
Drug Descriptions

Ubamatamab (REGN4018) is a bispecific antibody that binds MUC16 (CA125) on tumor cells and CD3 on T-cells to stimulate T-cell killing of MUC16-expressing tumor cells (AACR; Cancer Res 2018;78(13 Suppl):Abstract nr 1777, PMID: 31217340).

DrugClasses CD3 Antibody 119 MUC16 Targeted Therapy 10
CAS Registry Number 2305629-50-7
NCIT ID C153129

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Therapy Name Drugs Efficacy Evidence Clinical Trials
Bevacizumab + Sarilumab + Ubamatamab Bevacizumab Sarilumab Ubamatamab 0 1
Cemiplimab + Fianlimab + Sarilumab + Ubamatamab Cemiplimab Fianlimab Sarilumab Ubamatamab 0 1
Cemiplimab + Ubamatamab Cemiplimab Ubamatamab 0 2
Pegylated liposomal doxorubicin + Sarilumab + Ubamatamab Pegylated liposomal doxorubicin Sarilumab Ubamatamab 0 1
REGN5668 + Sarilumab + Ubamatamab REGN5668 Sarilumab Ubamatamab 0 1
REGN5668 + Ubamatamab REGN5668 Ubamatamab 0 1
Sarilumab + Tocilizumab + Ubamatamab Sarilumab Tocilizumab Ubamatamab 0 0
Sarilumab + Ubamatamab Sarilumab Ubamatamab 0 1
Ubamatamab Ubamatamab 0 2


Additional content available in Icon for CKB-BoostCKB BOOST