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Drug Name | Onvansertib |
Trade Name | |
Synonyms | PCM-075|PCM 075|NMS-P937 |
Drug Descriptions |
Onvansertib (PCM-075) is an ATP-competitive inhibitor of PLK1, which may result in cell cycle arrest, apoptosis, reduced tumor cell proliferation and colony formation in culture, and decreased tumor formation in mouse models (PMID: 22319201, PMID: 32017934, PMID: 32183025). |
DrugClasses | PLK1 Inhibitor 18 |
CAS Registry Number | 1034616-18-6 |
NCIT ID | C143162 |