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Drug Name | RMC-4630 |
Trade Name | |
Synonyms | RMC-4630-02|SAR442720|SAR 442720 |
Drug Descriptions |
RMC-4630 is an inhibitor of SHP2 (PTPN11) that prevents MAPK signaling and cell growth (PMID: 31727671). |
DrugClasses | SHP2 Inhibitor 20 |
CAS Registry Number | NA |
NCIT ID | C155850 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Adagrasib + RMC-4630 | Adagrasib RMC-4630 | 0 | 1 |
Cobimetinib + RMC-4630 | Cobimetinib RMC-4630 | 0 | 1 |
LY3214996 + RMC-4630 | LY3214996 RMC-4630 | 0 | 1 |
Osimertinib + RMC-4630 | Osimertinib RMC-4630 | 0 | 1 |
Pembrolizumab + RMC-4630 | Pembrolizumab RMC-4630 | 0 | 1 |
RMC-4630 | RMC-4630 | 0 | 1 |
RMC-4630 + Sotorasib | RMC-4630 Sotorasib | 0 | 2 |