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Drug Name Subasumstat
Trade Name
Synonyms TAK981|TAK 981|TAK-981
Drug Descriptions

Subasumstat (TAK-981) is a small molecule inhibitor of the SUMO-activating enzyme (SAE), which may lead to activation of anti-tumor immune response and inhibition of tumor growth (PMID: 37420267).

DrugClasses
CAS Registry Number 1858276-04-6
NCIT ID C156270

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Avelumab + Subasumstat Avelumab Subasumstat 0 1
Cetuximab + Subasumstat Cetuximab Subasumstat 0 1
Daratumumab and hyaluronidase-fihj + Subasumstat Daratumumab and hyaluronidase-fihj Subasumstat 0 1
Mezagitamab + Subasumstat Mezagitamab Subasumstat 0 1
Pembrolizumab + Subasumstat Pembrolizumab Subasumstat 0 1
Rituximab + Subasumstat Rituximab Subasumstat 0 1
Subasumstat Subasumstat 0 2
Subasumstat + Trametinib Subasumstat Trametinib 0 0


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