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Drug Name | Daratumumab and hyaluronidase-fihj |
Trade Name | Darzalex Faspro |
Synonyms | Daratumumab/rHuPH20|HuMax-CD38-rHuPH20|darzalex/rHuPH20 |
Drug Descriptions |
Darzalex Faspro (Daratumumab and hyaluronidase-fihj) is a combination of the anti-CD38 antibody Daratumumab with hyaluronidase, which may be administered subcutaneously (PMID: 32213342). Darzalex Faspro (Daratumumab and hyaluronidase-fihj) is FDA approved as a monotherapy or in combination with lenalidomide and dexamethasone, or with pomalidomide and dexamethasone, or with bortezomib and dexamethasone, or with bortezomib, melphalan, and prednisone, or with Kyprolis (carfilzomib) and dexamethasone, or with bortezomib, lenalidomide, and dexamethasone for patients with multiple myeloma, and in combination with bortezomib, cyclophosphamide and dexamethasone in patients with newly diagnosed light chain amyloidosis (FDA.gov). |
DrugClasses | CD38 Antibody 20 |
CAS Registry Number | NA |
NCIT ID | C156401 |