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| Drug Name | MRTX1719 |
| Trade Name | |
| Synonyms | MRTX-1719|MRTX 1719|BMS 986504|BMS986504|BMS-986504|BMS986504|Navlimetostat |
| Drug Descriptions |
MRTX1719 inhibits the PRMT5-MTA complex, which potentially results in reduced tumor growth (PMID: 35041419). |
| DrugClasses | PRMT5 Inhibitor 21 |
| CAS Registry Number | 2630904-45-7 |
| NCIT ID | C187048 |
| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Adagrasib + MRTX1719 | Adagrasib MRTX1719 | 0 | 0 |
| Fluorouracil + Irinotecan + MRTX1719 + Oxaliplatin | Fluorouracil Irinotecan MRTX1719 Oxaliplatin | 0 | 1 |
| Gemcitabine + MRTX1719 + Nab-paclitaxel | Gemcitabine MRTX1719 Nab-paclitaxel | 0 | 2 |
| MRTX-1133 + MRTX1719 | MRTX-1133 MRTX1719 | 0 | 0 |
| MRTX0902 + MRTX1719 | MRTX0902 MRTX1719 | 0 | 0 |
| MRTX1719 | MRTX1719 | 0 | 5 |
| MRTX1719 + Olaparib | MRTX1719 Olaparib | 0 | 1 |
| MRTX1719 + Pembrolizumab | MRTX1719 Pembrolizumab | 0 | 1 |