MK-2010
Drug Detail

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Drug Name MK-2010
Trade Name
Synonyms LM-299|LM 299|LM299|MK2010|MK 2010
Drug Descriptions

MK-2010 (LM-299) is a bispecific antibody targeting PDCD1 (PD-1) and VEGF, which potentially inhibits tumor growth (Cancer Res (2026) 86 (8_Supplement): CT057; NCT06650566).

DrugClasses PD-L1/PD-1 antibody 138 VEGF Antibody 17
CAS Registry Number NA
NCIT ID C228602

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Belzutifan + MK-2010 Belzutifan MK-2010 0 1
Carboplatin + MK-2010 + Nab-paclitaxel Carboplatin MK-2010 Nab-paclitaxel 0 1
Carboplatin + MK-2010 + Paclitaxel Carboplatin MK-2010 Paclitaxel 0 1
Carboplatin + MK-2010 + Pemetrexed Disodium Carboplatin MK-2010 Pemetrexed Disodium 0 1
Cisplatin + Gemcitabine + MK-2010 Cisplatin Gemcitabine MK-2010 0 1
Cisplatin + MK-2010 + Pemetrexed Disodium Cisplatin MK-2010 Pemetrexed Disodium 0 1
Fluorouracil + Leucovorin + MK-2010 + Oxaliplatin Fluorouracil Leucovorin MK-2010 Oxaliplatin 0 1
Fluorouracil + Levoleucovorin + MK-2010 + Oxaliplatin Fluorouracil Levoleucovorin MK-2010 Oxaliplatin 0 1
MK-2010 MK-2010 0 2
MK-2010 + Raludotatug deruxtecan MK-2010 Raludotatug deruxtecan 0 1
MK-2010 + Sacituzumab tirumotecan MK-2010 Sacituzumab tirumotecan 0 1


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