LM-299
Drug Detail

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Drug Name LM-299
Trade Name
Synonyms LM 299|LM299|MK2010|MK-2010|MK 2010
Drug Descriptions

LM-299 is a bispecific antibody targeting PDCD1 (PD-1) and VEGF, which potentially inhibits tumor growth (Cancer Res (2026) 86 (8_Supplement): CT057; NCT06650566).

DrugClasses PD-L1/PD-1 antibody 138 VEGF Antibody 17
CAS Registry Number NA
NCIT ID C228602

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Belzutifan + LM-299 Belzutifan LM-299 0 1
Carboplatin + LM-299 + Nab-paclitaxel Carboplatin LM-299 Nab-paclitaxel 0 1
Carboplatin + LM-299 + Paclitaxel Carboplatin LM-299 Paclitaxel 0 1
Carboplatin + LM-299 + Pemetrexed Disodium Carboplatin LM-299 Pemetrexed Disodium 0 1
Cisplatin + Gemcitabine + LM-299 Cisplatin Gemcitabine LM-299 0 1
Cisplatin + LM-299 + Pemetrexed Disodium Cisplatin LM-299 Pemetrexed Disodium 0 1
Fluorouracil + Leucovorin + LM-299 + Oxaliplatin Fluorouracil LM-299 Leucovorin Oxaliplatin 0 1
Fluorouracil + Levoleucovorin + LM-299 + Oxaliplatin Fluorouracil LM-299 Levoleucovorin Oxaliplatin 0 1
LM-299 LM-299 0 2
LM-299 + Raludotatug deruxtecan LM-299 Raludotatug deruxtecan 0 1
LM-299 + Sacituzumab tirumotecan LM-299 Sacituzumab tirumotecan 0 1


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