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Drug Name | Vandetanib |
Trade Name | Caprelsa |
Synonyms | ZD6474|AZD6474|AZD 6474 |
Drug Descriptions |
Caprelsa (vandetanib) is a multi-tyrosine kinase inhibitor with activity against VEGFR, EGFR, RET, SRC, and ABL1 kinases, potentially resulting in decreased tumor growth (PMID: 25031937, PMID: 25490448). Caprelsa (vandetanib) is FDA approved for use in medullary thyroid cancer (FDA.gov). |
DrugClasses | ABL1 Inhibitor 8 EGFR Inhibitor (Pan) 62 RET Inhibitor 53 SRC Inhibitor 31 VEGFR Inhibitor (Pan) 36 |
CAS Registry Number | 443913-73-3 |
NCIT ID | C2737 |