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Drug Name Infigratinib
Trade Name Truseltiq
Synonyms BGJ398|BGJ-398|BGJ 398
Drug Descriptions

Truseltiq (infigratinib) is a pan-FGFR inhibitor, which inhibits tumor angiogenesis and tumor cell proliferation (PMID: 31109923, PMID: 30101387).

DrugClasses FGFR Inhibitor (Pan) 26
CAS Registry Number 872511-34-7
NCIT ID C88302

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Therapy Name Drugs Efficacy Evidence Clinical Trials
ABT-737 + Infigratinib ABT-737 Infigratinib 3 0
Afatinib + Infigratinib Afatinib Infigratinib 0 0
Alpelisib + Infigratinib Alpelisib Infigratinib 2 1
Atezolizumab + Bevacizumab + Infigratinib Atezolizumab Bevacizumab Infigratinib 0 1
Binimetinib + Encorafenib + Infigratinib Binimetinib Encorafenib Infigratinib 0 1
Buparlisib + Infigratinib Buparlisib Infigratinib 1 0
Cabozantinib + Infigratinib Cabozantinib Infigratinib 0 0
Cisplatin + Gemcitabine + Infigratinib + Nab-paclitaxel Cisplatin Gemcitabine Infigratinib Nab-paclitaxel 0 1
Crizotinib + Infigratinib Crizotinib Infigratinib 0 0
Dasatinib + Infigratinib Dasatinib Infigratinib 4 0
Deltarasin + Infigratinib Deltarasin Infigratinib 0 0
Encorafenib + Infigratinib Encorafenib Infigratinib 0 1
Fluorouracil + Infigratinib Fluorouracil Infigratinib 0 0
Fluorouracil + Infigratinib + Irinotecan + Oxaliplatin Fluorouracil Infigratinib Irinotecan Oxaliplatin 0 1
Fulvestrant + Infigratinib + Palbociclib Fulvestrant Infigratinib Palbociclib 0 1
Ganetespib + Infigratinib Ganetespib Infigratinib 0 0
Gefitinib + Infigratinib Gefitinib Infigratinib 0 0
Ibrutinib + Infigratinib Ibrutinib Infigratinib 0 0
Imatinib + Infigratinib Imatinib Infigratinib 6 1
Infigratinib Infigratinib 178 15
Infigratinib + Lapatinib Infigratinib Lapatinib 0 0
Infigratinib + Navitoclax Infigratinib Navitoclax 1 0
Infigratinib + Olaparib Infigratinib Olaparib 0 0
Infigratinib + ONO-7475 + Osimertinib Infigratinib ONO-7475 Osimertinib 0 0
Infigratinib + Oxaliplatin Infigratinib Oxaliplatin 0 0
Infigratinib + Pelitinib Infigratinib Pelitinib 0 0
Infigratinib + Pictilisib Infigratinib Pictilisib 1 0
Infigratinib + Sapanisertib Infigratinib Sapanisertib 0 0
Infigratinib + Talazoparib Infigratinib Talazoparib 0 0
Infigratinib + Tamoxifen Infigratinib Tamoxifen 0 1
Infigratinib + Tepotinib Infigratinib Tepotinib 0 0
Infigratinib + Trabectedin Infigratinib Trabectedin 1 0
Infigratinib + Trametinib Infigratinib Trametinib 6 0
Infigratinib + Vandetanib Infigratinib Vandetanib 0 0


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