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Drug Name GSK2636771
Trade Name
Synonyms GSK-2636771|GSK 2636771
Drug Descriptions

GSK2636771 is a selective inhibitor of PIK3CB, which potentially increases apoptosis and decreases growth in tumors expressing PI3K beta (PMID: 28645941, PMID: 31371342).

DrugClasses PIK3CB inhibitor 8
CAS Registry Number 1372540-25-4
NCIT ID C106261

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Therapy Name Drugs Efficacy Evidence Clinical Trials
A66 + GSK2636771 A66 GSK2636771 1 0
Alpelisib + Encorafenib + GSK2636771 Alpelisib Encorafenib GSK2636771 1 0
Alpelisib + GSK2636771 Alpelisib GSK2636771 1 0
Binimetinib + GSK2636771 Binimetinib GSK2636771 2 0
Encorafenib + GSK2636771 Encorafenib GSK2636771 2 0
Encorafenib + GSK2636771 + unspecified IGF-1R antibody Encorafenib GSK2636771 unspecified IGF-1R antibody 1 0
Enzalutamide + GSK2636771 Enzalutamide GSK2636771 1 0
GSK2636771 GSK2636771 8 2
GSK2636771 + NVP-AEW541 GSK2636771 NVP-AEW541 2 0
GSK2636771 + Paclitaxel GSK2636771 Paclitaxel 1 0
GSK2636771 + Pembrolizumab GSK2636771 Pembrolizumab 1 1
GSK2636771 + unspecified IGF-1R antibody GSK2636771 unspecified IGF-1R antibody 1 0
GSK2636771 + unspecified PD-1 antibody GSK2636771 unspecified PD-1 antibody 1 0


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