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Drug Name NVP-AEW541
Trade Name
Synonyms
Drug Descriptions

NVP-AEW541 is a small molecule inhibitor of IGF1R that blocks IGF-I-mediated signaling, therefore inhibits tumor cell growth (PMID: 15050915, PMID: 30718793).

DrugClasses IGF-1R Inhibitor 17
CAS Registry Number 475489-16-8
NCIT ID NA

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Alpelisib + NVP-AEW541 Alpelisib NVP-AEW541 1 0
AZD6482 + Binimetinib + Encorafenib + NVP-AEW541 AZD6482 Binimetinib Encorafenib NVP-AEW541 1 0
AZD6482 + Binimetinib + NVP-AEW541 AZD6482 Binimetinib NVP-AEW541 1 0
AZD6482 + Encorafenib + NVP-AEW541 AZD6482 Encorafenib NVP-AEW541 1 0
AZD6482 + NVP-AEW541 AZD6482 NVP-AEW541 2 0
AZD8055 + NVP-AEW541 AZD8055 NVP-AEW541 0 0
Everolimus + NVP-AEW541 Everolimus NVP-AEW541 0 0
GSK2636771 + NVP-AEW541 GSK2636771 NVP-AEW541 2 0
NVP-AEW541 NVP-AEW541 0 0
NVP-AEW541 + Pictilisib NVP-AEW541 Pictilisib 2 0


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